Your body makes most of its cholesterol at night. Taking Simvastatin in the evening will target the time when cholesterol production is at its greatest.

Unlike Atorvastatin and Rosuvastatin, Simvastatin is a short-acting statin. This means that Simvastatin is present in the body only for a short time. Taking Simvastatin at night ensures that the medication works at its best.

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