HIV PEP Singapore | Emergency Post-Exposure Prophylaxis Within 72 Hours

Key Information

HIV PEP (Post-Exposure Prophylaxis) is an emergency treatment taken within 72 hours after possible HIV exposure to reduce infection risk. In Singapore, PEP requires a doctor’s assessment and a 28-day medication course. Sire provides confidential online consultations with Singapore-licensed doctors for urgent HIV PEP assessment, prescription, and discreet access when clinically appropriate.

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Doctor holding a red HIV awareness ribbon representing HIV prevention and PEP treatment in Singapore

What is HIV PEP (Post-Exposure Prophylaxis) in Singapore?

HIV Post Exposure Prophylaxis (PEP) is an emergency medical treatment used after a potential exposure to HIV. It involves a 28-day course of antiretroviral (ARV) medications designed to stop the virus from establishing infection in the body.

PEP is not a routine prevention method. Instead, it is used only in urgent, time-sensitive situations where there has been a meaningful risk of HIV exposure. The key principle of HIV PEP Singapore treatment is speed – the earlier it is started, the higher the effectiveness.

How HIV PEP Works

After HIV enters the body, it begins replicating rapidly within the first hours to days. PEP works by:

When taken correctly and started early, HIV PEP significantly reduces the risk of infection. However, it must be taken consistently for the full 28-day course to be effective.

HIV PEP Singapore Access

In Singapore, HIV PEP is only available via doctor prescription. A medical assessment is required to determine:

At Sire, patients can access confidential online consultations with Singapore-licensed doctors for urgent HIV PEP assessment. If suitable, treatment can be arranged promptly with discreet delivery or self-collection options.

Important Limitations of PEP

PEP is effective only when used correctly:

PEP should always be followed by appropriate HIV testing as advised by your doctor.

How HIV PEP Works & What to Expect

HIV PEP treatment involves a 28-day daily course of antiretroviral medication prescribed after clinical evaluation.

Infographic showing how HIV PEP medication works, treatment steps, and expected outcomes for emergency HIV prevention in Singapore

Treatment process

Strict adherence is essential. Missing doses may reduce effectiveness.

Is HIV PEP safe?

Modern HIV PEP medications are generally well tolerated. Some patients may experience:

These side effects are usually short-lived and resolve after completion of treatment.

Doctor oversight is essential

At Sire, all HIV PEP prescriptions are managed by Singapore-licensed doctors trained in sexual health and infectious disease risk assessment. We prioritise urgent cases within the critical 72-hour window.

When Should HIV PEP Be Started?

The timing of HIV PEP is the most important factor affecting effectiveness.

Recommended timing:

PEP becomes less effective as time passes because HIV replication may already have progressed beyond prevention.

What if I am unsure when exposure happened?

A doctor will evaluate:

If PEP is not appropriate, alternative testing or prevention strategies may be recommended.

How to Get HIV PEP in Singapore with Sire

Accessing HIV PEP quickly is critical. Sire provides a streamlined telemedicine pathway for urgent assessment and treatment.

Step-by-step infographic showing how to access HIV PEP in Singapore through Sire including online consultation, prescription, and medication delivery

Step 1: Urgent online consultation

Book a same-day or urgent video consultation with a Singapore-licensed doctor. Your exposure risk will be assessed confidentially.

Step 2: Clinical evaluation & testing (if needed)

Your doctor may recommend:

These ensure safe prescription of medication.

Step 3: Prescription & access

If HIV PEP is clinically indicated:

All care is handled confidentially in accordance with Singapore medical regulations.

HIV Testing, Safety Monitoring & Clinical Care

Before and after HIV PEP, testing plays a key role in ensuring accurate diagnosis and safety.

Baseline testing (before or immediately after starting PEP)

Doctors may recommend:

These help ensure medication safety and establish a baseline.

Follow-up testing schedule

Follow-up testing is important because HIV has a window period where early infection may not be immediately detectable.

Why follow-up matters

Even when PEP is taken correctly, testing ensures:

Additional STI screening

Patients with potential HIV exposure may also be tested for:

Early detection allows timely treatment and prevents complications.

Why Choose Sire?


With 15 years of experience, we support your health goals with reliable care delivered by our Singapore-licensed doctors.

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Skip clinic waiting rooms and forget app downloads. Simply access your account securely through our website, anytime.

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Consult with our licensed doctors online and receive your treatment delivered discreetly to you, with same-day delivery available.

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Enjoy flexible, quality healthcare with no long-term commitments. Book appointments, adjust your plan, or cancel anytime — hassle-free.

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Meet Our Doctor

Dr. Bosty Chan is a medical doctor with over 10 years of clinical experience in the United Kingdom and Singapore. He graduated from the University of Aberdeen, Scotland, and is a Member of the Royal College of Surgeons (Edinburgh). He has a clinical interest in telemedicine, digital health, and men’s health and holds a Certificate in Andrology (Singapore) from the Singapore Society of Men’s Health.



Dr Chan serves as the lead physician at Sire and Dame, discreet telemedicine platforms based in Singapore, where he focuses on accessible, technology-enabled healthcare.

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Dr Bosty Chan

Medical Director – Sire & Dame (Cloud Clinic)

MBChB (UK), MRCS (Edinburgh), Cert. in Andrology (Men’s Health)

Sire’s Easy Telemedicine Process

Discreet consults and doorstep delivery. We’ve made men’s healthcare as simple as it should be.

Survey

Complete a quick online health questionnaire and connect with our licensed Singapore doctor via a secure video consultation.

Consult

Our doctor reviews your health profile and, if appropriate, prescribes a clinically-proven treatment plan tailored to your needs.

Delivery & Follow-Up

Your medication is shipped in discreet packaging with same-day delivery or self-collection. Our care team is here to support you.

Common Questions About HIV PEP Singapore

We’ve got you covered.

HIV PEP should be started as soon as possible, ideally within 24 hours and no later than 72 hours after exposure.

Yes. HIV PEP can be accessed through telemedicine consultations with Singapore-licensed doctors who assess suitability before prescribing.

When started early and taken correctly for 28 days, HIV PEP can significantly reduce the risk of HIV infection.

Missing doses may reduce effectiveness. You should contact your doctor immediately for advice rather than stopping treatment.

Yes. Follow-up HIV testing is required at recommended intervals (commonly 4 weeks and 3 months) to confirm results.

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