Weight Loss
for Men

Weight loss can be effective and sustainable. Most importantly, you are in safe hands. We help you get the ball rolling. Losing excess weight is gaining health – and so much more.

  • Prescribed by doctors, clinically proven

  • FDA & HSA-approved treatment

  • Up to 10-20% weight loss

  • Long-term safety & effectiveness

  • 24/7 support

We will ask some questions about your symptoms and health to see if treatment is right for you.

Why Weight Management Matters to SIRE

“Every weight loss journey is different. At SIRE, weight management is more than losing weight. We are on a mission to help men regain confidence and control in their lives.”

Dr Bosty Chan
Founder & Clinical Lead

Yes. Weight loss treatments at SIRE begin with a medical evaluation by our MOH-licensed doctors. All weight loss treatments prescribed are HSA-approved and in accordance with MOH guidelines. Our doctors take a personalised approach, we monitor your weight loss journey regularly – you are not alone.

Answered by Dr. Bosty Chan

There is a lower defined BMI cut-off among Asians. Weight loss treatments can be recommended for Singaporean men with:

  • BMI of 23 kg/m2 or more with at least one weight-related medical problem such as high blood pressure, type 2 diabetes or high cholesterol or
  • BMI of 27.5 kg/m2 or more

Our doctors will assess your eligibility and recommend the best treatment for you.

Answered by Dr. Bosty Chan

Very often, we try to lose weight with pure motivation working on our diet and exercise. This is usually hard to maintain and we get discouraged when we do not achieve our weight loss goals.

Using weight loss treatments prescribed at SIRE can help you to reach your weight loss goals more quickly than exercise and diet alone. This can boost your confidence to continue to develop healthy lifestyle habits, making weight loss changes that last.

Answered by Dr. Bosty Chan

It is not mandatory to follow a strict diet and exercise programme. However, we strongly recommend making healthy lifestyle choices such as exercising regularly and eating a balanced diet.

At SIRE, we prioritise your overall well-being through setting realistic goals and avoiding extreme measures. We also provide evidence-based recommendations that are essential for a successful weight loss journey.

Answered by Dr. Bosty Chan

The Weight Loss Revolution for You

Weight management does not have to be complicated.
We make it safe and simple for you.

Simple Losses, for Big Gains in Life

Shedding just 5% of excess weight brings profund health benefits and Reduce your risk of chronic health conditions

Getting the right start is so important. At SIRE, we help Singaporeans find the appropriate treatment to begin shedding the extra pounds in a safe and sustainable way.


Diet and exercise fads are short-term. Medical solutions for weight loss are evidence-based with long-term prospects.
New advancements in weight loss medications have demonstrated up to 22.5% weight loss when added to lifestyle changes.


The higher your BMI, the higher your health risks for diabetes, high blood pressure, sleep apnea, joint pain, erectile dysfunction and so much more. Re-assess your health today to safeguard your future


Imagine your current lifestyle: long working hours, extended periods of sitting, and the daily grind. It’s no wonder your weight loss journey feels increasingly challenging. Embrace a world where you feel lighter, happier, and full of vitality.

SIRE is Singapore’s leading men’s health clinic for sexual wellness. Weight loss has been proven to enhance sexual performance, address erectile dysfunction, improve fertility, stamina and so much more. We help you bring your A game from the boardroom to the bedroom.

Perhaps this is your first attempt at losing weight or perhaps there have been multiple attempts – we do not judge. Getting started on the right treatment helps you find the right motivation to form healthy and sustainable habits.

We are here to support you and champion your change.

Simple Losses, for Big Gains in Life

Shedding just 5% of excess weight brings profund health benefits and Reduce your risk of chronic health conditions

Getting the right start is so important. At SIRE, we help Singaporeans find the appropriate treatment to begin shedding the extra pounds in a safe and sustainable way.


Diet and exercise fads are short-term. Medical solutions for weight loss are evidence-based with long-term prospects.
New advancements in weight loss medications have demonstrated up to 22.5% weight loss when added to lifestyle changes.

SIRE is Singapore’s leading men’s health clinic for sexual wellness. Weight loss has been proven to enhance sexual performance, address erectile dysfunction, improve fertility, stamina and so much more. We help you bring your A game from the boardroom to the bedroom.

Perhaps this is your first attempt at losing weight or perhaps there have been multiple attempts – we do not judge. Getting started on the right treatment helps you find the right motivation to form healthy and sustainable habits.

We are here to support you and champion your change.


The higher your BMI, the higher your health risks for diabetes, high blood pressure, sleep apnea, joint pain, erectile dysfunction and so much more. Re-assess your health today to safeguard your future.


Imagine your current lifestyle: long working hours, extended periods of sitting, and the daily grind. It’s no wonder your weight loss journey feels increasingly challenging. Embrace a world where you feel lighter, happier, and full of vitality.

Embrace the Simplicity of SIRE’s Online Weight Loss Solution

Imagine the hasslae of taking time off work, searching for clinics, waiting in crowded rooms, visiting doctors – on repeat. It’s tiring and time-consuming. With SIRE, we help you find sustainable solutions at the comfort of your home, on your schedule.

Connect with qualified medical professionals online, receive personalised solutions, and have your medications delivered as quickly within four hours in 3 simple steps:

*MOH requires all HCI-registered telemedicine clinics to perform a single video consultation

Panbesy thesire.sg

Panbesy


Short-acting suppressant

$2.30/dose

from

  • Approved by FDA & HSA for weight loss
  • Appetite suppressant, reduces food intake
  • Average weight loss of 5-10% seen over 12-36 weeks
Orlistat thesire.sg

Orlistat


Dietary fat-binder

$3.10/dose

from

  • Approved by FDA & HSA for weight loss
  • Reduces the amount of fat your body absorbs from food
  • Average weight loss of 8-10% seen over 1 year
Saxenda thesire.sg

Saxenda


Daily weight loss injection

$15.25/dose

from

  • Approved by FDA & HSA for weight loss
  • Regulate appetite by mimicking hormone GLP-1
  • Average weight loss of 5-20% seen over 1 year
Duromine thesire.sg

Duromine


Long-acting suppressant

$2.45/dose

from

  • Approved by FDA & HSA for weight loss
  • Appetite suppressant, reduces food intake
  • Average weight loss of 5-10% seen over 12-36 weeks
Contrave – Craving reduction tablet thesire.sg

Contrave


Craving reduction

$2.18/dose

from

  • Approved by FDA & HSA for weight loss
  • Craving reduction, appetite control
  • Average weight loss of 9-13% seen over 56 weeks

Real Men, Real Results

What you can expect from your weight loss journey with SIRE

SIRE vs. Others: What Sets Us Apart?

Many weight loss or slimming pills sold online are unsafe or do not work. Do not risk your health
over unproven and unsafe treatments. At SIRE, we are a MOH-licensed telemedicine clinic using
only FDA & HSA approved treatments, backed by science.

SIREX online shop
MOH-licensed telemedicine clinicVSUnknown sources
Medications approved by FDA and HSA for weight lossVS“Word-of-mouth” pills that work or miracle slimming pills
Lifestyle recommendations backed by scienceVSLifestyle recommendations based on weight loss fads and trends
Free, discreet deliveryVSLong clinic waits, pharmacy queues
24/7 customer supportVSIncognito Google searches
Trusted by more than 10,000 Singaporean men, rated 4.8 on Google ReviewsVSLack of regulations and credibility
0%

of Singaporeans are overweight and 10% are obese

What they are saying about us

Trouble shedding kilos? A weight loss treatment that works
with your biology, not against it, to unlock your willpower.

Very quick response and prompt consultation. Delivery of medication is fast too. Good experience.
Kai Chng
Great service and the fast delivery is very efficient. Doctors appointments are made swiftly and professionally.
Benjamin Low
The consultation by the doctor is fantastic and easy. Getting the medication sent to me is very convenient and save my time.
Chng Guan Poh, Desmond

SIRE Featured on

The logos featured on this website are the copyrighted and registered trademarks of their respective owners.
All trademarks and names are used for demonstration purposes only and do not imply endorsement.

We answer all your burning weight questions

Having obesity increases the risks of many different health problems. It can also make it harder for you to do things that people who are at a healthy weight can do easily.

People with obesity are more likely to get diabetes, heart disease, cancer and lots of other health problems. People with obesity also have a shorter lifespan and a lower quality of life than people of normal weight. This is why it is important to keep your weight in a healthy range.

At Sire, we help you get the ball rolling with our weight loss treatments – take control today.

Losing weight offers numerous benefits for men and promotes healthy masculinity. Shedding excess weight can improve cardiovascular health, lower the risk of obesity-related conditions, such as diabetes and hypertension, enhance physical endurance, and boost self-confidence.

Weight loss can lead to increased energy levels, improved sleep quality, and reduced joint pain. It also positively impacts mental health, reducing stress and anxiety. Adopting a healthier lifestyle fosters self-discipline and resilience, setting a positive example for others.

Embracing weight loss not only improves overall well-being but also empowers men to embrace a healthier, more fulfilling life.

At Sire, we help you achieve your every goal.

If you would like to lose weight, you can start by talking to our doctors at Sire. We can help you make a plan to lose weight in a healthy way.

In general, to lose weight, you have to eat fewer calories and move your body more.

Studies have compared different types of diet. There is no specific diet that is better than any other. Any diet that reduces the number of calories you eat can help you to lose weight, as long as you stick with it. You should try to find an eating pattern that can work for you. A dietitian can help you make healthy changes to your diet while making sure that you get the nutrients your body needs.

Physical activity works the same way. You can walk, run, swim, dance, or even just move your arms while sitting. Even gentle forms of exercise are good for your health. For weight loss, the important thing is to increase the number of calories you burn by moving more. And you have to keep doing the extra activity.

If you go on a diet for a short time, or increase your activity for a while, you might lose weight. But you will regain the weight if you go back to your old habits. Weight loss is about changing your habits for the long term.

The best way to start is to make small changes and stick with them. Then, little by little, you can add new changes that you also stick with.

At Sire, we give weight to your weight loss frustrations – with our weight loss treatments, we can help you get the ball rolling.

There are medicines and surgery to help with weight loss. These treatments are only for people who have not been able to lose weight through diet and exercise.

Weight loss treatments do not replace diet and exercise. People who receive medical treatments have to also work on building healthy lifestyle habits.

Medical treatments for weight loss can be safe and effective when used under the professional guidance of our doctors at Sire, start your journey with us today!

Weight loss medicines work by reducing your appetite or by changing the way you absorb fat from your food.

They can be safe and effective when prescribed under the professional advice of our doctors at Sire, always discuss your concerns and your goals with us.

Duromine and Panbesy contain the active ingredient Phentermine. As such, they work similarly and have a similar side effect profile.

There are currently no studies available to compare the effectiveness of Duromine and Panbesy directly.

The main difference between Duromine and Panbesy is the type of Phentermine it contains.
Duromine contains Phentermine as an ion-exchange resin complex while Panbesy contains Phentermine hydrochloride.

As an ion-exchange resin complex, Duromine releases Phentermine continuously over a 10 to 14 hour period. In comparison, Panbesy is absorbed over 3-4.4 hours.

It is likely that Duromine provides a longer-lasting and constant appetite suppression throughout the day since it is released more slowly and over a longer period. With Panbesy, its effect on appetite suppression may not be as long-lasting.

Also, with Phentermine being slowly absorbed into the bloodstream in smaller amounts over a longer period, the risk of side effects with Duromine may be lower as compared to Panbesy.

Always discuss with your doctor at Sire to find out if Duromine or Panbesy is right for you – we are on this journey together.

Many herbal weight loss medicines are unsafe or do not work. Some weight loss medicines are also sold over the internet. They can contain harmful ingredients and be unsafe. It is always advisable to check with a doctor or pharmacist before you take any herbal or non-prescription weight loss medicines or supplements.

At Sire, safe and effective weight loss treatments are available – your health and your safety is our top priority.

At SIRE, our doctors will do a full assessment of your health and medical history and work with your weight loss goals to select the best weight loss treatment for you.
Here are some questions you can ask our doctors:

  • About how much weight can I expect to lose, and how long will that take? This depends on the treatment. There are different types of medications to help with weight loss. The amount of weight loss and how long it takes to lose weight is different for each one.
  • What are the risks of treatment? All weight loss medicines like any other medicines can have side effects. Always discuss your concerns with your doctor.
  • What changes will I need to make to my diet and lifestyle? Weight loss treatments are not “shortcuts” that you can take to avoid making lifestyle changes. No single weight loss treatment works on its own, you have to also make changes to how you eat and how active you are. At SIRE, we help you make realistic and achievable goals.
It is not recommended to buy weight loss medications online as it can be risky and unsafe.
Online pharmacies may sell counterfeit or expired drugs, which can be dangerous for your health. It is also difficult to verify the authenticity and safety of these medications when purchased online.

Moreover, most weight loss medications require a prescription from a licensed healthcare provider, and buying them online without a prescription is illegal. Additionally, online purchases may not come with the necessary instructions and warnings regarding dosage and side effects.

If you are considering using weight loss medications, it is recommended to consult with a licensed healthcare provider who can evaluate your health condition and prescribe the appropriate medication. This will ensure that you are using safe and effective medication for your weight loss journey.

At Sire, we are a MOH-licensed telemedicine clinic in Singapore. All medications are from HSA-registered sources.

Yes. Weight loss treatments can be prescribed remotely by a doctor upon a video consultation. SIRE is a MOH-licensed telemedicine clinic, a detailed medical assessment and consultation is mandatory before treatment is prescribed.